Methodical recommendation for the laboratory lesson

SEMEY STATE MEDICAL ACADEMY

Specialty: 0501301General medicine

Discipline: chemistry

Chair: of chemistry and technology of medicine

Higher base medical education, course – 1

Topic №9: Acidity and basidity of organic compounds. Reactionary ability of alcohols, phenols, toils and amines.

Semey 2007

Approved

on the chair meeting from “_____”____________2007.

Protocol № ____

Head of the chair of chemistry and technology of medicine,

prof. __________ Gavrilenko I.V

1.Topic№9: Acidity and basidity of organic compounds. Reactionary ability of alcohols, phenols, toils and amines.

2.Aim: to study: the main positions to theory of acidity and basidity of organic compounds on Breasted and Lowry; the quantitative characteristic of acidity and basidity of organic compounds (К_а, рК_а, К_b and рК_b); the influence of the nature of the atom in acid centre, stabilities of anion, organic radical and solvent on acidity and basidity of organic compounds.

3.Objectives of teaching: to teach give comparative qualitative and quantitative characteristic of acidity and basidity of organic compounds.

4. Basic questions:

1. The notion about acidity and basidity of organic compounds on Breasted and Lowry

2. Classification of acid: ОН-, SH-, NH-, CH–acids

3. Quantitative and qualitative evolution of acidity and basidity: К_а, рК_а и К_b, рК_b.

4. Comparative characteristic of acidity properties of alcohol, thiolos, phenols and carboxylic acid..

5. Influence number of the functional groups on acidity of organic compounds.

6. Role undivided electron pair of heteroatom in manifestation main properties of amines, alcohol, thiolos.

7. Lewis acids and bases.

5. Methods of teaching:

The determining initial level knowledge’s of student on chemistry. The conversation and questioning on topic of the lesson. Fulfilling the laboratory work and protection of the report.