Знаков). 50 to 200 mg/day orally in 1 or 2 divided doses

50 to 200 mg/day orally in 1 or 2 divided doses.

Usual Adult Dose for Congestive Heart Failure:

25 mg/day orally. Increase or decrease based on response and evidence of hyperkalemia.

Usual Adult Dose for Primary Hyperaldosteronism:

Initial dose: 100 mg orally once a day. This dosage may be divided into two daily doses, and increased as tolerated every two to three days to a maximum recommended total daily dose of 400 mg. It is recommended that the dosage be titrated to decrease sodium retention, hypertension, weakness, hypokalemia, and any other signs or symptoms of primary hyperaldosteronism in this patient.

If this patient has an adrenal adenoma or carcinoma, the lowest possible Aldactone dosage should be given while waiting for surgery. Adrenal hyperplasia, however, usually does not respond to surgery, and chronic spironolactone therapy is recommended.

Patients with adrenal hyperplasia often require other antihypertensive therapy to control their associated hypertension.

Usual Pediatric Dose for Hypertension:

Neonates: 1 to 3 mg/kg/day orally every 12 to 24 hours.

Children: 1.5 to 3.3 mg/kg/day or 60 mg/m2/day orally in divided doses every 6 to 12 hours not to exceed 100 mg/day.

Usual Pediatric Dose for Primary Hyperaldosteronism Diagnosis:

Children: 100 to 400 mg/m2/day orally in 1 to 2 divided doses.

What other drugs will affect Aldactone?

Taking this medicine with other drugs that make you dizzy or lower your blood pressure can worsen these effects. Ask your doctor before taking Aldactone with a narcotic pain medicine, muscle relaxer, or medicine for anxiety or seizures.

Other drugs may interact with spironolactone, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Not all side effects for Aldactone may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to spironolactone: oral tablet