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Brand Names: Amaryl

What is Amaryl?

Amaryl (glimepiride) is an oral diabetes medicine that helps control blood sugar levels.

Amaryl is used together with diet and exercise to treat type 2 diabetes. Insulin or other diabetes medicines are sometimes used in combination with Amaryl if needed.

Amaryl may also be used for purposes not listed in this medication guide.

Important information

Do not use Amaryl if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

Before taking Amaryl, tell your doctor if you are allergic to sulfa drugs, or if you have heart disease, liver disease, kidney disease, an enzyme deficiency (G6PD), adrenal or pituitary gland problems, or if you are under-nourished.

Take care not to let your blood sugar get too low. Low blood sugar (hypoglycemia) can occur if you skip a meal, exercise too long, drink alcohol, or are under stress. Symptoms include headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating. Carry hard candy or glucose tablets with you in case you have low blood sugar. Other sugar sources include orange juice and milk. Be sure your family and close friends know how to help you in an emergency.

Before taking this medicine

You should not use Amaryl if you are allergic to glimepiride, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

To make sure Amaryl is safe for you, tell your doctor if you have:

heart disease;

liver or kidney disease;

an allergy to sulfa drugs;

an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);

adrenal or pituitary gland problems; or

if you are under-nourished.

FDA pregnancy category C. It is not known whether Amaryl will harm an unborn baby. Similar diabetes medications have caused severe hypoglycemia in newborn babies whose mothers had used the medication near the time of delivery. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

See also: Pregnancy and breastfeeding warnings (in more detail)